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InnoChem Inc
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FUJIFILM
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FUJIFILM
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BASF
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Merck KGaA
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HiMedia Laboratories
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honeywell international
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Sinopharm ltd
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BDH Chemicals Ltd
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Image Search Results
Journal: International Journal of Nanomedicine
Article Title: Enhanced transdermal permeability and drug deposition of rheumatoid arthritis via sinomenine hydrochloride-loaded antioxidant surface transethosome
doi: 10.2147/IJN.S188842
Figure Lengend Snippet: ( A ) The chemical structure of sinomenine hydrochloride, phospholipid, and ascorbyl palmitate. ( B ) The ethosomal sizes were prepared by different stirring velocities and time on the basis of the stirring-injection method. ( C ) The ethosomal sizes were prepared by different injection velocities, ultrasound time, and probe ultrasound time based on ultrasound-injection method. ( D ) The capsulation efficiency with different edge activators (* P <0.05 vs E). ( E ) The deformability indexes under 0.3 and 0.5 MPa were measured by self-made equipment on the right. (* P < 0.05 vs E). ( F ) The cumulative permeation rates in vitro of control (sinomenine hydrochloride normal saline solution), E, and TE1, containing different concentrations of sodium deoxycholate, and AS-TE. (* P <0.05 vs control and TE1 containing 5.0 mg/mL of sodium deoxycholate). ( G ) The TEM images of E, TE1, and AS-TE. Abbreviations: E, ethosome; TE, transethosomes (ethosome containing sodium deoxycholate (TE1), tween-80 (TE2) and oleic acid (TE3)); AS-TE, antioxidant surface transethosome.
Article Snippet:
Techniques: Injection, In Vitro, Control, Saline
Journal: International Journal of Nanomedicine
Article Title: Enhanced transdermal permeability and drug deposition of rheumatoid arthritis via sinomenine hydrochloride-loaded antioxidant surface transethosome
doi: 10.2147/IJN.S188842
Figure Lengend Snippet: The composition of nanocarrier in 1 mL aqueous solution and physicochemical properties (Mean ± SD, n=3)
Article Snippet:
Techniques:
Journal: International Journal of Nanomedicine
Article Title: Enhanced transdermal permeability and drug deposition of rheumatoid arthritis via sinomenine hydrochloride-loaded antioxidant surface transethosome
doi: 10.2147/IJN.S188842
Figure Lengend Snippet: The representative chromatograms of ( A ) plasma pharmacokinetic and ( B ) micro-dialysis sample. ( C ) The blood concentration-time profiles of healthy rabbits (control: sinomenine hydrochloride solution gel). ( D ) The diameters of knee joint and inflammation cytokines of rheumatoid arthritis model rabbits (* P < 0.05 vs control: healthy rabbits). ( E ) The synovial fluid concentration-time profiles of rheumatoid arthritis model rabbits (* P < 0.05 vs TE1). Abbreviations: E, ethosome; TE1, transethosomes (ethosome containing sodium deoxycholate (TE1)); AS-TE, antioxidant surface transethosome.
Article Snippet:
Techniques: Clinical Proteomics, Concentration Assay, Control
Journal: International Journal of Nanomedicine
Article Title: Enhanced transdermal permeability and drug deposition of rheumatoid arthritis via sinomenine hydrochloride-loaded antioxidant surface transethosome
doi: 10.2147/IJN.S188842
Figure Lengend Snippet: ( A ) The photographs of normal and rheumatoid arthritis ankles and the diameter and girth-time profiles of rheumatoid arthritis ankles injected with 150 and 200 μL of complete Freund’s adjuvant (CFA). ( B ) The rat weight, diameter, and girth-time profiles with different treatments. (* P < 0.05 vs negative control group and + P < 0.05 vs normal control) ( C ) The erythrocyte sedimentation rate (ESR) and inflammation cytokines after 24 days of treatment. (* P < 0.05 vs negative control group and + P < 0.05 vs normal control) (Red triangle: the time of modeling, blue triangle: the time of treatment). Abbreviations: E, ethosome; TE1, transethosomes (ethosome containing sodium deoxycholate (TE1)); AS-TE, antioxidant surface transethosome.
Article Snippet:
Techniques: Injection, Adjuvant, Negative Control, Control, Sedimentation
Journal: International Journal of Nanomedicine
Article Title: Enhanced transdermal permeability and drug deposition of rheumatoid arthritis via sinomenine hydrochloride-loaded antioxidant surface transethosome
doi: 10.2147/IJN.S188842
Figure Lengend Snippet: ( A ) The bone micro-computed tomography (CT) scan images and the red areas showed the bone injury. ( B ) The bone volumes, bone surfaces, and specific surface areas after 24 days of treatment. Abbreviations: E, ethosome; TE1, transethosomes (ethosome containing sodium deoxycholate (TE1)); AS-TE, antioxidant surface transethosome; i.g., intragastric administration.
Article Snippet:
Techniques: Micro-CT, Computed Tomography